Thus, antibiotic resistance genes spread among the bacteria
Now for the first time, Structure of the transport apparatus shown It allows the spread of antibiotic resistance genes among bacteria. A better understanding of how these antibiotic resistance genes spread can help stop or at least reduce the spread of antibiotic resistance microorganisms in the future.
In a new study involving experts from University College London (UCL) was analyzed as the so-called bacterial conjugation allows unidirectional transfer of DNA from the donor cell to the recipient cell. This is the main way Spread of antibiotic resistance genes in bacterial populations.
The corresponding results of the study were published in the English-language journal “Nature”.
Why antibiotic resistance is growing
Scientists stress that growing antibiotic resistance poses a serious threat to all of humanity. Antibiotic resistance is a naturally occurring phenomenon, but it is caused excessive and incorrect use of antibiotics amplified in humans and animals.
According to experts at Robert Koch Institute (RKI) propagates any use of antibiotics the emergence of resistance. Indeed, resistant bacteria do not survive such treatment, while resistant bacteria survive and spread continue to multiply.
Therefore, it is logical that antibiotic-resistant pathogens often occur where this is particularly important a lot of antibiotics are usedas in hospitals and agriculture.
Problems in the treatment of infectious diseases
The growth of antibiotic-resistant bacteria is threatened Treatment options for many infectious diseases, according to researchers involved in the current study. RKI also emphasizes that infections with resistant pathogens usually spread more difficult to treat and one complete a more complex course be able.
“We are in a global crisis of antimicrobial resistance, threatening the devastation of healthcare systems around the world – the World Health Organization identifies antimicrobial resistance as one of the greatest threats to global health, food safety and current development.“Explains the author of the study Professor Gabriel Waksman in a recent press release.
Although the development of antibiotic resistance cannot be prevented, understanding exactly how bacteria are able to exchange genes could open up approaches to their prevention. Combating the spread of antibiotic resistance genes.
The current research work contributes decisively to this and with the help of cryo-electron microscopy shows how exactly Antibiotic resistance is spreading in bacterial populations. An extremely large protein-protein interaction network plays a crucial role here. (as)
Author and resource information
This text corresponds to the specifications of the medical literature, medical recommendations and current studies and has been reviewed by medical professionals.
- Abhinav K. Vadakkepat, Adam Redzej, Natalya Lukoyanova, Clasien Oomen, Nathalie Braun et al .: Cryo-EM structure of the type IV secretory system; in: Nature (verfentlicht 22.06.2022), Nature
- University College London: New hope to stop the spread of antibiotic resistance (veröffentlicht 23.06.2022), UCL
- Robert Koch Institute: Basic Knowledge of Antibiotic Resistance (as of May 9, 2019), RKI
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.