The second multi-resistant variant: a person becomes infected with “super gonorrhea”

The second multi-resistant variant
Man infected with “super gonorrhea”

In Austria, researchers have identified a strain of bacteria that causes gonorrhea and is resistant to many different antibiotics. The man contracted her during unprotected sex in Cambodia.

Researchers from all over the world have identified a gonococcal strain that is multiple resistant for the second time. Bacteria lead to what is known as gonorrhea, a sexually transmitted disease that is also colloquially known as “gonorrhea.” The variant found in April comes from a traveler returning from Cambodia, writes a research team led by Sonja Pleininger from the Austrian Agency for Health and Food Safety (AGES) in a publication in the journal Eurosurveillance. The man had sex without a condom with a prostitute in Cambodia five days before the symptoms began.

The infection is caused by bacteria. Pathogens Neisseria gonorrhoeae they mainly affect the mucous membranes. The men then experience itching and a discharge of purulent secretions from the urethra. They also experience pain when urinating, but asymptomatic or mild, as in many infected women, is very rare in men.

Nevertheless, every infection should be treated, otherwise there may be consequent damage such as arthritis, skin changes or even heart valves or meningitis. In women, infertility or life-threatening pelvic inflammation is possible as a consequential injury. It can lead to malformations of the unborn child in pregnant women. If the disease is not treated, it can also spread.

Usually, a bacterial infection is easily treated with some antibiotics. In the current case, standard therapy initially failed. Although the man was better, the tests remained positive.

Six substances are no longer effective

Then he became an exciter Neisseria gonorrhoeae examined in more detail. In the laboratory, he proved to be highly resistant to azithromycin. Resistance to ceftriaxone, cefixime, cefotaxime, ciprofloxacin and tetracycline, all antibiotics used in gonorrhea, have also been identified. Multiple resistances not only make it difficult to treat the patient, but also make the pathogen a dangerous “super gonorrhea.”

The pathogen has proven to be variable in the past. There are now a number of mutations that are resistant to many drugs that have been used successfully so far. In treatment, physicians currently rely primarily on the administration of ceftriaxone, which is often prescribed in combination with azithromycin. Azithromycin resistance has increased rapidly in Europe in recent years. In addition, several ceftriaxone-resistant strains have been identified in several European countries, the researchers said.

Researchers stress that if new offspring are now circulating who can be better protected from all available treatment options, they should be considered a greater risk to public health. In the worst case, the infection cannot be cured in the future. This danger must be addressed by measures such as condom use, rapid diagnosis and easily accessible, effective and inexpensive treatment options.

Better monitoring is needed

The man was eventually cured with a combination of antibiotics given twice a day for one week. However, the Cambodian sex worker failed to track down. Experts fear that other people could become infected with the resistant pathogen.

To prevent further infections and the emergence of multi-resistant pathogens, experts call on authorities in Asia in particular to activate and intensify surveillance systems. The first multidrug-resistant gonorrhea pathogen was detected in a man in the United Kingdom in 2018. He, too, most likely became infected while in Asia. In response to the growing number of resistant Neisseria gonorrhoeae-As early as 2020, pathogens introduced a laboratory requirement for the reporting of resistant pathogens.

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