Better understanding of the risk of developing dementia
When people at the same time Type 2 diabetes and heart disease lead, doubled this you risk of developing dementia. Prevention of diabetes and cardiovascular disease could also help reduce the risk of dementia.
In a new study by experts from Karolinska Institutet in Sweden, the combined effect of cardiometabolic diseases on the risk of developing dementia was investigated. The results were published in Alzheimer’s & Dementia.
Data from 2,500 participants were evaluated
For new research work Daten aus der Swedish national study on aging and care used. Overall, the data from 2 500 healthy people over 60 who did not suffer from dementia at the beginning of the study.
At the beginning of the study, the incidence of cardiometabolic diseases was assessed using Medical documentation and clinical examinations determined. The participants then stayed for a while medically monitored for twelve years.
In addition, participants had to undergo cognitive tests in order to do so Changes in cognitive abilities and development of dementia according to experts observed.
How does dementia develop?
Dementia develops very slowly and lasts for decades. The disease first manifests as gradual cognitive declinewhich can only be determined in cognitive tests.
Poor memory as a sign of dementia
According to the team, the next step is and cognitive impairment in which the persons concerned notice themselves that they are under bad memory they suffer but are still able to take care of themselves. Ultimately, full-blown dementia develops and the patient no longer manages daily life on their own.
Cardiometabolic diseases risk factors for dementia
The so-called cardiometabolic diseases (type 2 diabetes, ischemic heart disease, congestive heart failure, atrial fibrillation and stroke) are considered the most important risk factors for dementiaresearchers report.
Yet “Few studies have examined how the coexistence of several of these diseases affects the risk of dementia, and this is exactly what we wanted to examine in our study.“Explains the author of the study Abigail Dove in the press release.
A double risk of dementia has been identified
Data analysis showed the presence more than one cardiometabolic disease cognitive decline rate significantly accelerated. This has also led to a doubling of the risk of developing dementia, the researchers report.
That The risk increased with the number of diseases and a specific combinations of diseases It seems to increase the risk of dementia particularly strongly. “In our study, combinations of diabetes / heart disease and diabetes / heart disease / stroke were most detrimental to cognitive functionDove reports.
Experts add that, however, people who only cardiometabolic disease he had no significantly higher risk of dementia exposed.
This can prevent the development of dementia
“That’s good news. The study shows that the risk only increases if someone has at least two of these diseasesHe emphasizes Dove. Dementia can be prevented by preventing the development of another disease.
Prevention in middle age
The study also found that the correlation between cardiometabolic disease and dementia risk was stronger in participants under the age of 78.
“We should therefore focus on the prevention of cardiometabolic diseases from middle age, because the risk of cognitive failure and dementia seems to be higher in those who develop cardiometabolic diseases earlier in life.“, yes Dove.
In the future, the team hopes to find out more about the mechanism that underpins this association. That’s what the effects are supposed to do genetic factors examined and brain imaging determined how Cardiometabolic diseases damage the brain be able. (as)
Author and resource information
This text conforms to the specifications of the medical literature, medical recommendations and current studies and has been reviewed by medical experts.
- Abigail Dove, Anna Marseglia, Ying Shang, Giulia Grande, Davide Liborio Vetrano et al .: Cardiometabolic multimorbidity accelerates cognitive decline and dementia progression; in: Alzheimer’s disease and dementia (veröffentlicht 16.06.2022), Alzheimer’s disease and dementia
- Karolinska Institutet: Diabetes and cardiovascular disease increase the risk of dementia (published 16.06.2022), Karolinska Institutet
This article contains general advice only and should not be used for self-diagnosis or treatment. It can’t replace a doctor’s visit.