Vienna, April 1, 2019 / PRNewswire / – Outpatients with positive COVID-19 are at increased risk of neurodegenerative diseases compared to people who have tested negative for the virus. This is shown by a new study presented today at the 8th Congress of the European Academy of Neurology (EAN).
VIENNA, June 24, 2022 / PRNewswire / – A study analyzing the health data of more than half of the Danish population found that those who tested positive for Covid-19 were at increased risk of Alzheimer’s disease, Parkinson’s disease and had ischemia. strokes.
Of the 919,731 people tested for Covid-19 in the study, the researchers found that 43,375 people who tested positive had a 3.5-fold higher risk of developing Alzheimer’s disease, a 2.6-fold increased risk of Parkinson’s disease, a 2.7-fold increased risk ischemic stroke and a 4.8-fold increased risk of intracerebral haemorrhage. While neuroinflammation may contribute to the accelerated development of neurodegenerative diseases, the authors have noted the implications of the scientific focus on the long-term consequences of Covid-19.
The study analyzed Danish hospitalized and outpatient patients between February 2020 and November 2021, as well as patients with influenza from the corresponding period before the pandemic. The researchers used statistical methods to calculate the relative risk and the results were stratified according to hospitalization status, age, gender and comorbidities.
Dr Pardis Zarifkar, lead author of a study at the Rigshospitalet Department of Neurology in Copenhagen, Denmark, explained: “More than two years after the Covid-19 pandemic broke out, the exact nature and development of Covid-19’s impact on neurological diseases is unknown and still uncharacterized. Previous studies have found an association with neurological syndromes, but it is not yet known whether Covid-19 also affects the incidence of certain neurological diseases and whether it differs from other respiratory infections. “
However, the increased risk of most neurological disorders was not higher in Covid-19-positive patients than in those diagnosed with influenza or other respiratory diseases. Patients with Covid-19 had a 1.7-fold higher risk of ischemic stroke compared with influenza and bacterial pneumonia in patients over 80 years of age.
The incidence of other neurodegenerative diseases, such as multiple sclerosis, myasthenia gravis, Guillain-Barré syndrome and narcolepsy, did not increase after Covid-19, influenza or pneumonia.
Dr Pardis Zarifkar added: “These results advance our understanding of the long-term effects of Covid-19 on the body and the role that infections play in neurodegenerative diseases and strokes.”